Description

Methyl 2-(2-Oxoindolin-5-Yl)Acetate is a high-purity pharmaceutical intermediate and versatile synthetic building block. This compound is valued for its role as a key precursor in the synthesis of complex bioactive molecules, particularly those targeting neurological and oncological pathways. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-quality raw materials for advanced synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of oxindole-based drug candidates and active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the development of compounds targeting kinase inhibition and neurodegenerative disease pathways.
• Oncology Research: Serves as a building block for small molecule inhibitors and targeted cancer therapies.
• Chemical Synthesis: Employed in organic synthesis for the construction of complex heterocyclic frameworks and functionalized indolinone derivatives.
• Process Development: Utilized in route scouting, optimization, and scale-up activities for new chemical entities (NCEs).
• Reference Standard: Suitable for use as an analytical standard in quality control and method development laboratories.

Basic Information

Product Name	Methyl 2-(2-Oxoindolin-5-Yl)Acetate
CAS No.	109737-05-5
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	5-(2-Methoxy-2-oxoethyl)indolin-2-one; Methyl (2-oxo-2,3-dihydro-1H-indol-5-yl)acetate; 5-(Carboxymethyl)oxindole methyl ester; 2-Oxo-5-indolineacetic acid methyl ester; 1H-Indole-5-acetic acid, 2,3-dihydro-2-oxo-, methyl ester; Methyl 5-indolin-2-oneacetate; Methyl 2-oxo-2,3-dihydro-1H-indole-5-acetate
EINECS	Contact for details

Quality Control

Our Methyl 2-(2-Oxoindolin-5-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.