Description

Tetramethylammonium Triacetoxyborohydride is a versatile and highly effective reducing agent, specifically designed for selective reductions in organic synthesis. Its value lies in its ability to function as a mild and chemoselective hydride donor, often under conditions where other borohydride reagents are too harsh or non-selective. This makes it an indispensable tool for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries, where precise control over reaction outcomes is critical.

Application

• Selective Carbonyl Reduction: Preferred for the chemoselective reduction of aldehydes and ketones in the presence of other sensitive functional groups like esters, epoxides, or halides.
• Pharmaceutical Intermediate Synthesis: Key reagent in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for creating chiral alcohol centers.
• Asymmetric Synthesis: Used in conjunction with chiral catalysts or auxiliaries to produce enantiomerically enriched alcohols, a cornerstone of modern drug development.
• Fine Chemical Manufacturing: Employed in the production of specialty chemicals, flavors, fragrances, and advanced materials requiring high-purity intermediates.
• Reductive Amination: Effective for the one-pot conversion of carbonyl compounds to amines via imine or iminium ion intermediates.
• Academic & Process Research: A staple reagent in R&D laboratories for developing new synthetic methodologies and optimizing chemical processes.

Basic Information

Product Name	Tetramethylammonium Triacetoxyborohydride
CAS No.	109704-53-2
Molecular Formula	C10H24BNO6
Molecular Weight	265.12 g/mol
Synonyms	Tetramethylammonium Triacetoxyhydroborate; N,N,N-Trimethylmethanaminium Triacetoxyborohydride; TMAB; Tetramethylammonium Borohydride Acetate Complex; Triacetoxyborohydride Tetramethylammonium Salt; (Acetoxy)borate(1-), Trihydrotri-, Tetramethylammonium; Tetramethylazanium Triacetoxyboranuide
EINECS	Contact for details

Quality Control

Our Tetramethylammonium Triacetoxyborohydride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and titration methods, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and efficacy. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.