Description

Dihydromorphinone n-Oxide is a specialized chemical compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and analytical profiling of complex opioid derivatives. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in neuropharmacology and analgesic studies. The material demands stringent quality control to ensure reliability in sensitive applications.

Application

• Pharmaceutical Intermediate: Key building block in the research-scale synthesis of novel opioid receptor ligands and related pharmacologically active molecules.
• Analytical Reference Standard: Used for method development, calibration, and quantification in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) for forensic and pharmaceutical analysis.
• Biochemical Research: Employed in in vitro studies to investigate metabolic pathways, enzyme interactions, and receptor binding affinities within the central nervous system.
• Process Development: Serves as a model compound for optimizing chemical processes, including oxidation reactions and purification techniques relevant to fine chemical manufacturing.

Basic Information

Product Name	Dihydromorphinone n-Oxide
CAS No.	109648-80-8
Molecular Formula	C17H19NO5
Molecular Weight	317.34 g/mol
Synonyms	Dihydromorphinone N-Oxide; Dihydromorphone N-Oxide; 14-Hydroxydihydromorphinone N-Oxide; Oxymorphone N-Oxide (dihydro); 4,5α-Epoxy-3,14-dihydroxy-17-methylmorphinan-6-one N-Oxide
EINECS	Contact for details

Quality Control

Our Dihydromorphinone n-Oxide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.