Description

Pentanedioic Acid, 2-(Mercaptomethyl)- is a specialized bifunctional organic compound featuring both a carboxylic acid and a thiol (mercapto) group on its molecular backbone. This unique structure makes it a valuable intermediate for synthesizing complex molecules, particularly in the pharmaceutical and fine chemical sectors. It is primarily sought after by research and development chemists and process engineers for applications in drug discovery, peptide synthesis, and as a building block for functional polymers and ligands.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring thiol- or disulfide-based functional groups.
• Peptide Modification: Used to introduce thiol handles into peptides for conjugation, labeling, or creating cyclic peptide structures.
• Ligand Synthesis: Serves as a precursor for chelating agents and ligands used in catalysis and metal ion sequestration.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polymers with specific mechanical or chemical properties.
• Bioconjugation: Facilitates the attachment of biomolecules to surfaces, nanoparticles, or other molecules via thiol-reactive chemistry.
• Research & Development: A versatile reagent in organic synthesis for exploring new chemical entities and reaction pathways in academic and industrial labs.

Basic Information

Product Name	Pentanedioic Acid, 2-(Mercaptomethyl)-
CAS No.	109333-27-9
Molecular Formula	C6H10O4S
Molecular Weight	178.21 g/mol
Synonyms	2-(Mercaptomethyl)pentanedioic acid; 3-Mercaptomethylglutaric acid; 2-(Mercaptomethyl)glutaric acid; Glutaric acid, 2-(mercaptomethyl)-; MMGA; Mercaptomethylglutaric Acid
EINECS	Contact for details

Quality Control

Our Pentanedioic Acid, 2-(Mercaptomethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical-grade intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. Due to its sensitivity to oxidation, the container should be kept sealed and only opened under controlled conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.