Description

5-(2-Aminoethyl)Thiophene-2-Sulfonamide is a specialized organic intermediate featuring both a sulfonamide group and a primary amine separated by an ethylene linker from a thiophene ring. This unique bifunctional structure makes it a valuable building block for the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting enzymes where the sulfonamide moiety acts as a pharmacophore.
• Chemical Biology & Proteomics: Used in the development of chemical probes and activity-based protein profiling (ABPP) reagents due to its reactive amine handle.
• Material Science Research: Serves as a monomer or functionalization agent in the development of novel polymers and functional materials with specific electronic or binding properties.
• Agrochemical Synthesis: Employed in research for creating new herbicides or fungicides that leverage the thiophene-sulfonamide scaffold.
• Ligand Synthesis for Catalysis: The amine and sulfonamide groups can be utilized to construct chelating ligands for metal catalysts.

Basic Information

Product Name	5-(2-Aminoethyl)Thiophene-2-Sulfonamide
CAS No.	109213-13-0
Molecular Formula	C6H10N2O2S2
Molecular Weight	206.28 g/mol
Synonyms	2-Thiophenesulfonamide, 5-(2-aminoethyl)-; 5-(2-Aminoethyl)-2-thiophenesulfonamide; 2-Aminoethyl-5-thiophenesulfonamide; 5-(2-Aminoethyl)thiophene-2-sulfonic acid amide; N-(2-Aminoethyl)thiophene-2-sulfonamide; AE-TSA
EINECS	Contact for details

Quality Control

Our 5-(2-Aminoethyl)Thiophene-2-Sulfonamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under a dry inert atmosphere for long-term storage and to minimize exposure to humid air. Recommended storage temperature is 2-8°C for prolonged stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.