Description

1H-Indole-3-Carboxylic Acid, 4-Nitro-, Methyl Ester is a high-purity, synthetically valuable nitro-substituted indole derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis for research and development. It is primarily utilized by fine chemical manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and material science sectors to develop novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Organic Synthesis Building Block: The nitro and ester functional groups make it a versatile substrate for further chemical transformations, such as reductions and cross-couplings.
• Material Science: Employed in research for creating novel organic electronic materials and functional dyes.
• Biochemical Research: Acts as a probe or inhibitor in enzymatic studies due to its structural similarity to natural indoles.

Basic Information

Product Name	1H-Indole-3-Carboxylic Acid, 4-Nitro-, Methyl Ester
CAS No.	109175-08-8
Molecular Formula	C10H8N2O4
Molecular Weight	220.18 g/mol
Synonyms	Methyl 4-Nitro-1H-indole-3-carboxylate; 4-Nitroindole-3-carboxylic Acid Methyl Ester; 1H-Indole-3-carboxylic acid, 4-nitro-, methyl ester; Methyl 4-nitroindole-3-carboxylate; 4-Nitro-1H-indole-3-carboxylic acid methyl ester; 3-Carbomethoxy-4-nitroindole; 4-Nitroindole-3-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Carboxylic Acid, 4-Nitro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistent performance as a synthesis intermediate. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.