Description

4-{[3-(Methoxycarbonyl)-4,5,6,7-Tetrahydro-1-Benzothiophen-2-Yl]Amino}-4-Oxobutanoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique tetrahydrobenzothiophene scaffold. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile handle for further chemical elaboration. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates and novel chemical entities.
• API Synthesis: Serves as a core structural component for the development of potential therapeutic molecules targeting various disease pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new pharmacophores.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4-{[3-(Methoxycarbonyl)-4,5,6,7-Tetrahydro-1-Benzothiophen-2-Yl]Amino}-4-Oxobutanoic Acid
CAS No.	109164-45-6
Molecular Formula	C15H17NO5S
Molecular Weight	323.36 g/mol
Synonyms	4-{[3-(Methoxycarbonyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]amino}-4-oxobutanoic acid; 2-[(3-Carbomethoxy-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)amino]-2-oxoacetic acid (related structure); Tetrahydrobenzothiophene-2-carboxamide derivative; Succinamic acid, N-(3-methoxycarbonyl-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-; 109164-45-6; 4-Oxo-4-{[3-(methoxycarbonyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]amino}butanoic acid
EINECS	Contact for details

Quality Control

Our production of 4-{[3-(Methoxycarbonyl)-4,5,6,7-Tetrahydro-1-Benzothiophen-2-Yl]Amino}-4-Oxobutanoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.