Description

1-(Thiophen-2-Yl)Piperazine is a versatile heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new pesticides, herbicides, and fungicides due to its bioactive piperazine-thiophene core.
• Material Science Research: Serves as a precursor for organic semiconductors, ligands for catalysis, and monomers for specialty polymers.
• Chemical Biology & Proteomics: Employed as a linker or scaffold in the design of chemical probes and enzyme inhibitors for biological studies.
• Academic & Contract Research: Essential for method development and exploratory synthesis in university and CRO laboratory settings.
• Custom Synthesis & Scale-up: A starting material for contract manufacturing organizations (CMOs) producing kilogram to multi-ton quantities for client projects.

Basic Information

Product Name	1-(Thiophen-2-Yl)Piperazine
CAS No.	108768-19-0
Molecular Formula	C8H12N2S
Molecular Weight	168.26 g/mol
Synonyms	2-(1-Piperazinyl)thiophene; 2-Piperazin-1-ylthiophene; 1-(2-Thienyl)piperazine; 1-(Thiophen-2-yl)piperazine; Thiophen-2-yl-piperazine; N-(Thiophen-2-yl)piperazine; Piperazine, 1-(2-thienyl)-; 108768-19-0
EINECS	Contact for details

Quality Control

Our 1-(Thiophen-2-Yl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development and commercial projects requiring material that meets stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.