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Borane-Dicyclohexylphosphine Complex CAS NO 108756-88-3


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CAS No.:108756-88-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Borane-Dicyclohexylphosphine Complex is a versatile and highly reactive organoborane reagent, specifically a borane-phosphine adduct, widely used as a selective reducing agent and catalyst in organic synthesis. Its primary value lies in its ability to facilitate challenging reductions and serve as a stable source of borane for hydroboration reactions under controlled conditions. This complex is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries, where precise and selective chemical transformations are critical.

Application

  • Selective Reduction Agent: For the chemoselective reduction of carbonyl groups, including aldehydes, ketones, and acid chlorides, in the presence of other sensitive functional groups.
  • Hydroboration Catalyst/Reagent: Acts as a stable, easy-to-handle source of borane (BH3) for the hydroboration of alkenes and alkynes, a key step in synthesizing alcohols and other valuable intermediates.
  • Asymmetric Synthesis: Employed in chiral synthesis when used with chiral phosphine ligands or in conjunction with other chiral auxiliaries to produce enantiomerically enriched compounds.
  • Pharmaceutical Intermediate Manufacturing: A critical reagent in multi-step synthetic routes for active pharmaceutical ingredients (APIs) and complex drug candidates.
  • Polymer & Material Science: Used in the synthesis and modification of polymers, as well as in the surface functionalization of advanced materials.
  • Agrochemical Synthesis: Facilitates the production of complex molecules used in crop protection agents and herbicides.

Basic Information

Product Name Borane-Dicyclohexylphosphine Complex
CAS No. 108756-88-3
Molecular Formula C12H22P·BH3 or C12H25BP
Molecular Weight 196.12 g/mol
Synonyms Borane-Dicyclohexylphosphine; Dicyclohexylphosphine-Borane Complex; Dicyclohexylphosphine Borane; BH3-Dicyclohexylphosphine; Dicyclohexylphosphane-Borane (1:1); PCy2H·BH3; Borane-Phosphine Adduct; Borane Tertiary Phosphine Complex
EINECS Contact for details

Quality Control

Our Borane-Dicyclohexylphosphine Complex is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed to confirm identity, potency, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by NMR or titration), physical characteristics, and specific test results is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, this complex must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed and allowed to reach room temperature before opening to minimize moisture ingress.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (NMR/Titration) ≥ 95.0%
Melting Point Contact for details
Solubility Soluble in common organic solvents (THF, DCM, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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