Description

Phenyl 2,3,4-Tri-o-Acetyl-1-Thio-α-L-Rhamnopyranoside is a key thioglycoside intermediate, specifically designed for advanced synthetic chemistry applications. Its acetyl-protected rhamnose scaffold and phenylthio aglycone make it a versatile and reactive building block for constructing complex carbohydrate derivatives and glycoconjugates. This high-purity compound is essential for researchers and manufacturers in pharmaceutical development, glycobiology research, and the synthesis of novel bioactive molecules.

Application

• Glycosylation Reagent: A crucial building block for the stereoselective synthesis of α-linked rhamnose-containing oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediate: Used in the research and development of new therapeutic agents, including antibiotics, antivirals, and anti-cancer drugs that target carbohydrate-mediated processes.
• Glycobiology Probe Synthesis: Serves as a precursor for labeled (e.g., fluorescent, radioactive) rhamnose derivatives used to study biological recognition and enzyme activity.
• Carbohydrate Chemistry Research: A standard substrate for studying glycosidase enzymes and developing new glycosylation methodologies.
• Synthesis of Natural Products: Key intermediate in the total synthesis of complex natural products that contain L-rhamnose moieties.
• Glycolipid and Glycopeptide Synthesis: Employed in the preparation of structurally defined glycolipids and glycopeptides for immunological and biochemical studies.

Basic Information

Product Name	Phenyl 2,3,4-Tri-o-Acetyl-1-Thio-α-L-Rhamnopyranoside
CAS No.	108740-74-5
Molecular Formula	C18H22O7S
Molecular Weight	382.43 g/mol
Synonyms	Phenyl 1-Thio-α-L-rhamnopyranoside 2,3,4-Triacetate; 1-Thio-α-L-rhamnopyranoside, Phenyl, 2,3,4-Triacetate; Phenyl 2,3,4-Tri-O-acetyl-1-thio-α-L-rhamnopyranoside; α-L-Rhamnopyranoside, Phenyl 1-Thio-, 2,3,4-Triacetate; Phenyl 1-Thio-α-L-rhamnopyranoside Triacetate; Thioglycoside Donor L-Rhamnose Derivative; Acetylated Phenyl Thiormannoside
EINECS	Contact for details

Quality Control

Our Phenyl 2,3,4-Tri-o-Acetyl-1-Thio-α-L-Rhamnopyranoside is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, purity, and impurity profile. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.