Description

1-Fluoro-3-Iodo-Propane is a valuable bifunctional alkylating agent containing both fluorine and iodine atoms on a short propyl chain. This unique structure makes it a versatile and reactive intermediate for introducing fluorinated alkyl segments into target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials. Its reactivity profile allows for selective functionalization, enabling the construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, including potential antivirals, anticancer agents, and CNS-active compounds.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides where the introduction of fluorine can enhance biological activity, stability, and metabolic properties.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and fluorinated surface coatings.
• Ligand and Catalyst Development: Employed to synthesize fluorinated ligands for catalysis and molecular recognition applications.
• Radiochemistry: The iodine atom provides a potential handle for radioiodination, useful in developing diagnostic imaging agents.
• Organic Synthesis Reagent: A versatile reagent for nucleophilic substitution reactions, enabling chain extension and the introduction of functional groups in complex molecule synthesis.

Basic Information

Product Name	1-Fluoro-3-Iodo-Propane
CAS No.	108607-97-2
Molecular Formula	C3H6FI
Molecular Weight	187.98 g/mol
Synonyms	3-Iodo-1-fluoropropane; 1-Fluoropropyl-3-iodide; 3-Fluoropropyl iodide; Fluoropropyl iodide; Iodofluoropropane; Propane, 1-fluoro-3-iodo-; 1-Fluoro-3-iodopropane; F(CH2)3I
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-Iodo-Propane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Standard quality assurance includes rigorous analytical testing via GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat sources and incompatible materials. Due to its light-sensitive and highly volatile nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C for extended stability. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.9 g/mL
Boiling Point	~145-150°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.