Description

Allyl Tetraisopropylphosphorodiamidite is a specialized organophosphorus compound widely utilized as a key intermediate in organic synthesis. Its primary value lies in its role as a versatile phosphitylating agent, particularly in the synthesis of oligonucleotides and other phosphorus-containing fine chemicals. This product is essential for research and production facilities in the pharmaceutical, agrochemical, and advanced materials sectors seeking to build complex molecular architectures.

Application

• Oligonucleotide Synthesis: A critical phosphoramidite monomer for the solid-phase synthesis of DNA and RNA sequences in research and therapeutic development.
• Phosphorus Ligand Precursor: Serves as a building block for the preparation of chiral and achiral phosphorus ligands used in homogeneous catalysis.
• Pharmaceutical Intermediates: Employed in the synthesis of active pharmaceutical ingredients (APIs) that contain phosphorus, such as nucleotide analogs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where phosphorus chemistry is central to the mode of action.
• Material Science: Acts as a precursor for modifying surfaces or creating phosphorus-doped polymers and advanced materials.
• Chemical Research: A valuable reagent for academic and industrial R&D in developing new synthetic methodologies involving phosphorus (III) chemistry.

Basic Information

Product Name	Allyl Tetraisopropylphosphorodiamidite
CAS No.	108554-72-9
Molecular Formula	C13H29N2O2P
Molecular Weight	276.35 g/mol
Synonyms	Allyl N,N,N',N'-Tetraisopropylphosphorodiamidite; Tetraisopropyl Allylphosphorodiamidite; Allylphosphorodiamidic Acid Tetraisopropyl Ester; Phosphorodiamidous Acid, Allyl-, Tetraisopropyl Ester; P-Allyl-N,N,N',N'-tetraisopropylphosphorodiamidite; Allyl Tetraisopropyldiamidophosphite
EINECS	Contact for details

Quality Control

Our Allyl Tetraisopropylphosphorodiamidite is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Each lot is analyzed using advanced techniques including NMR and HPLC to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to maximize stability. This material is hygroscopic and easily oxidized; ensure containers are sealed immediately after use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.