Description

4-Trifluoromethylbenzyl Mercaptan is a specialized organosulfur compound featuring a benzyl mercaptan group substituted with a trifluoromethyl moiety. This unique structure makes it a valuable building block for synthesizing more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for creating novel active ingredients and advanced materials. The compound is supplied with a focus on high purity and batch-to-batch consistency to ensure reliable performance in sensitive synthetic applications.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group imparts desirable biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in catalysis, particularly in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the creation of novel polymers, liquid crystals, and organic electronic materials where fluorine substitution modifies physical properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	4-Trifluoromethylbenzyl Mercaptan
CAS No.	108499-24-7
Molecular Formula	C8H7F3S
Molecular Weight	192.20 g/mol
Synonyms	α-(Trifluoromethyl)benzenemethanethiol; (4-(Trifluoromethyl)phenyl)methanethiol; 4-(Trifluoromethyl)benzylthiol; p-(Trifluoromethyl)benzyl mercaptan; 1-(Trifluoromethyl)-4-(mercaptomethyl)benzene; 4-Trifluoromethylbenzenemethanethiol; 4-Trifluoromethyl-α-toluenethiol
EINECS	Contact for details

Quality Control

Every batch of 4-Trifluoromethylbenzyl Mercaptan is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including GC, HPLC, and NMR analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flame. Due to its sensitivity, allow the container to reach room temperature before opening to minimize moisture ingress and oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.