Description

n-Hydroxy-Thiophene-2-Carboxamidine is a specialized heterocyclic amidine derivative that serves as a versatile building block in advanced organic synthesis. Its unique molecular structure, featuring both a thiophene ring and a reactive amidoxime-like functional group, makes it a valuable intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting enzymes or receptors where the amidine moiety can act as a bioisostere.
• Agrochemical Research: Used in developing novel fungicides, herbicides, or insecticides, leveraging the thiophene scaffold for bioactive molecule design.
• Coordination Chemistry & Ligand Synthesis: Serves as a chelating ligand for metal ions in catalytic systems or for creating metal-organic frameworks (MOFs).
• Material Science Precursor: Employed in the synthesis of conductive polymers, organic semiconductors, or other functional organic materials where the thiophene unit is integral.
• Chemical Biology Probe Development: Useful for creating molecular probes to study biological processes due to its ability to form specific interactions.

Basic Information

Product Name	n-Hydroxy-Thiophene-2-Carboxamidine
CAS No.	108443-93-2
Molecular Formula	C5H6N2OS
Molecular Weight	142.18 g/mol
Synonyms	2-Thiophenecarboximidamide, N-hydroxy-; N-Hydroxy-2-thiophenecarboximidamide; (Hydroxyamino)(2-thienyl)methanimine; Thiophene-2-carboxamidine, N-hydroxy-; 2-Thienylcarboxamidoxime; 108443-93-2; N-Hydroxy-2-thiophenecarboxamidine
EINECS	Contact for details

Quality Control

Our n-Hydroxy-Thiophene-2-Carboxamidine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation, to ensure consistency and reliability for research and development purposes. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as assay purity and identity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.