Description

Cyclopropanemethanol, 2,2-Dichloro-α-Methyl-, (R*,S*)- (9Ci) is a specialized chiral building block featuring a cyclopropane ring substituted with dichloro and hydroxymethyl groups. This compound matters as a high-value intermediate for the synthesis of complex molecules, offering unique steric and electronic properties due to its strained ring system. It is needed by pharmaceutical, agrochemical, and advanced material research laboratories for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or with specific stereochemical requirements.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane moiety can contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Investigated as a monomer or cross-linking agent for producing polymers with unique thermal and mechanical properties derived from the rigid cyclopropane structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study enzyme mechanisms or protein-ligand interactions.

Basic Information

Product Name	Cyclopropanemethanol, 2,2-Dichloro-α-Methyl-, (R*,S*)- (9Ci)
CAS No.	108431-60-3
Molecular Formula	C5H8Cl2O
Molecular Weight	155.02 g/mol
Synonyms	2,2-Dichloro-α-methylcyclopropanemethanol; (R*,S*)-2,2-Dichloro-1-methylcyclopropanemethanol; 1-Cyclopropane-1-methanol, 2,2-dichloro-α-methyl-, (R*,S*)-; 2,2-Dichloro-1-methylcyclopropylmethanol; α-Methyl-2,2-dichlorocyclopropanemethanol
EINECS	Contact for details

Quality Control

Our Cyclopropanemethanol, 2,2-Dichloro-α-Methyl-, (R*,S*)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and transfers should be conducted under subdued light or in amber glass containers to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98:2 (R*,S* ratio)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.