Description

Trimethylsilyl-L(+)Rhamnose is a silylated derivative of the naturally occurring deoxy sugar L-rhamnose, specifically designed to enhance stability and reactivity for advanced synthetic applications. This compound is a crucial intermediate in carbohydrate chemistry, offering improved solubility in organic solvents and protection of hydroxyl groups during complex multi-step syntheses. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel glycosides, glycoconjugates, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex carbohydrate-based drugs, antiviral agents, and antibiotics.
• Glycoconjugate Synthesis: Used in the preparation of glycoproteins, glycolipids, and other biologically active conjugates for research and therapeutic development.
• Agrochemical Research: Serves as a precursor in the development of new sugar-based pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, chiral auxiliaries, and advanced materials requiring protected sugar moieties.
• Analytical Standard: Used as a reference standard in chromatographic analysis (HPLC, GC) for quality control and method development in carbohydrate analysis.
• Academic & Industrial R&D: Essential reagent for exploring new synthetic pathways in organic and medicinal chemistry laboratories.

Basic Information

Product Name	Trimethylsilyl-L(+)Rhamnose
CAS No.	108392-01-4
Molecular Formula	C15H34O5Si4
Molecular Weight	438.84 g/mol
Synonyms	L-Rhamnose, trimethylsilyl derivative; 6-Deoxy-L-mannose trimethylsilyl ether; Per-O-trimethylsilyl-L-rhamnose; TMS-L-Rhamnose; L-(+)-Rhamnose per(trimethylsilyl) ether; 1,2,3,4-Tetra-O-trimethylsilyl-6-deoxy-L-mannopyranose; (2R,3R,4R,5R)-2,3,4,5-Tetrakis(trimethylsilyloxy)-6-methyloxane
EINECS	Contact for details

Quality Control

Our Trimethylsilyl-L(+)Rhamnose is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) after opening to prevent decomposition. Ensure the storage area is well-ventilated and away from sources of heat and ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.