Description

5-Iodothiazole is a versatile halogenated heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to introduce the thiazole moiety with a reactive iodine handle for further functionalization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting infectious diseases, neurological disorders, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides that incorporate the bioactive thiazole ring.
• Material Science: Serves as a building block for creating functional organic materials, including liquid crystals, organic semiconductors, and photoactive compounds.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to form carbon-carbon bonds.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry for exploring new synthetic pathways and creating compound libraries.
• Ligand and Catalyst Preparation: Used in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	5-Iodothiazole
CAS No.	108306-61-2
Molecular Formula	C3H2INS
Molecular Weight	210.93 g/mol
Synonyms	5-Iodothiazole; Thiazole, 5-iodo-; 5-Iodo-1,3-thiazole; 5-Iodothiazole (CAS 108306-61-2); 1,3-Thiazole, 5-iodo-; Iodothiazole; 5-Iodo-thiazole
EINECS	Contact for details

Quality Control

Our 5-Iodothiazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.