Description

Methyl 2-[(2-Chloroacetyl)Amino]-3-(1H-Indol-3-Yl)Propanoate is a specialized synthetic intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the preparation of complex molecules, particularly those with indole-based pharmacophores. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Peptidomimetic Research: Serves as a building block for creating peptide analogs and mimetics due to its amino acid ester backbone and indole side chain.
• Agrochemical Development: Used in research for developing new crop protection agents and plant growth regulators.
• Bioconjugation Chemistry: Employed in the development of linker molecules and probes for biochemical and diagnostic applications.
• Academic & Institutional R&D: Utilized in university and contract research organization (CRO) laboratories for methodological studies and novel compound library generation.

Basic Information

Product Name	Methyl 2-[(2-Chloroacetyl)Amino]-3-(1H-Indol-3-Yl)Propanoate
CAS No.	108273-71-8
Molecular Formula	C14H15ClN2O3
Molecular Weight	294.73 g/mol
Synonyms	N-(2-Chloroacetyl)-L-tryptophan methyl ester; Methyl N-(2-chloroacetyl)-L-tryptophanate; L-Tryptophan, N-(2-chloroacetyl)-, methyl ester; (S)-Methyl 2-(2-chloroacetamido)-3-(1H-indol-3-yl)propanoate; 2-[(2-Chloroacetyl)amino]-3-(1H-indol-3-yl)propanoic acid methyl ester; Tryptophan derivative, chloroacetylated methyl ester; N-Chloroacetyltryptophan methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-[(2-Chloroacetyl)Amino]-3-(1H-Indol-3-Yl)Propanoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.