Description

4-Chloro-2-Phenylthiazole-5-Carbaldehyde is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting various enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides, fungicides, and insecticides, leveraging the bioactive thiazole core.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials, ligands for catalysis, and functional polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Chloro-2-Phenylthiazole-5-Carbaldehyde
CAS No.	108263-77-0
Molecular Formula	C10H6ClNOS
Molecular Weight	223.68 g/mol
Synonyms	4-Chloro-2-phenyl-1,3-thiazole-5-carboxaldehyde; 2-Phenyl-4-chlorothiazole-5-carbaldehyde; 5-Formyl-4-chloro-2-phenylthiazole; 4-Chloro-2-phenyl-5-thiazolecarboxaldehyde; (4-Chloro-2-phenyl-1,3-thiazol-5-yl)methanal; 108263-77-0; 4-Chloro-2-phenylthiazole-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2-Phenylthiazole-5-Carbaldehyde is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.