Description

8-Methoxy-2-Methyl-6,7-Methylenedioxy-1,2,3,4-Tetrahydroisoquinolin-4-Ol is a sophisticated tetrahydroisoquinoline derivative, a key structural motif in medicinal chemistry. This compound matters as a versatile and high-purity synthetic intermediate, enabling the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. Pharmaceutical R&D laboratories, agrochemical manufacturers, and advanced material scientists need this building block for its potential in creating compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential alkaloid-based drugs, including antitussive, analgesic, or central nervous system (CNS) active agents.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) in drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides or herbicides that leverage the isoquinoline structure for bioactivity.
• Biochemical Tool Compound: Acts as a precursor or reference standard in biochemical assays and pharmacological studies targeting specific enzyme or receptor pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic Research: Utilized in university and institutional labs for organic synthesis methodology development and the study of heterocyclic chemistry.

Basic Information

Item	Details
Product Name	8-Methoxy-2-Methyl-6,7-Methylenedioxy-1,2,3,4-Tetrahydroisoquinolin-4-Ol
CAS No.	108261-07-0
Molecular Formula	C₁₂H₁₅NO₄
Molecular Weight	237.25 g/mol
Synonyms	4-Hydroxy-8-methoxy-2-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-8-methoxy-2-methyl-6,7-methylenedioxyisoquinolin-4-ol; 8-Methoxy-2-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydro-4-isoquinolinol; THIQ derivative; Tetrahydroisoquinolinol derivative
EINECS	Contact for details

Quality Control

Our 8-Methoxy-2-Methyl-6,7-Methylenedioxy-1,2,3,4-Tetrahydroisoquinolin-4-Ol is produced under strict quality management systems. We offer material suitable for research and development, with typical purity grades exceeding 95% (HPLC). Each batch is characterized and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting key specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, maintaining the material at 2-8°C is recommended to ensure optimal stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.