Description

1H-3-Benzazepin-7-Ol,8-Bromo-2,3,4,5-Tetrahydro-3-Methyl-5-Phenyl-,Hydrobromide(1:1) is a high-purity, complex organic salt with the CAS number 108179-91-5. This compound serves as a critical advanced intermediate in pharmaceutical research and development, particularly for the synthesis of novel central nervous system (CNS) active agents. It is essential for medicinal chemists and process development scientists working in neuropharmacology and drug discovery.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel benzazepine-based drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic agents for CNS conditions.
• Process Development: Serves as a standard or starting material for scaling up synthetic routes in Active Pharmaceutical Ingredient (API) manufacturing.
• Biochemical Research: Employed as a ligand or probe in pharmacological assays to study receptor interactions and signaling pathways.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Custom Synthesis: A foundational compound for the custom synthesis of more complex, target-specific molecules for preclinical studies.

Basic Information

Product Name	1H-3-Benzazepin-7-Ol,8-Bromo-2,3,4,5-Tetrahydro-3-Methyl-5-Phenyl-,Hydrobromide(1:1)
CAS No.	108179-91-5
Molecular Formula	C17H19BrN2O • HBr
Molecular Weight	428.17 g/mol
Synonyms	8-Bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrobromide; 8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol HBr; SKF-77434 hydrobromide; 7-Hydroxy-8-bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide; 108179-91-5; (3R*,5S*)-8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol hydrobromide
EINECS	Contact for details

Quality Control

Our 1H-3-Benzazepin-7-Ol,8-Bromo-2,3,4,5-Tetrahydro-3-Methyl-5-Phenyl-,Hydrobromide(1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.