Description

Acrylamide-D5 CAS NO 108152-65-4 is a deuterium-labeled analog of acrylamide, where five hydrogen atoms are replaced with deuterium, serving as a crucial internal standard for precise analytical quantification. This high-purity isotopically labeled compound is essential for eliminating matrix effects and ensuring accurate, reliable results in sensitive mass spectrometry-based analyses. It is primarily required by analytical laboratories, contract research organizations (CROs), and pharmaceutical companies engaged in method development, residue testing, and metabolomic studies where trace-level detection of acrylamide is critical.

Application

• Internal Standard for LC-MS/MS and GC-MS: Used for the accurate quantification of acrylamide in food safety testing (e.g., in fried and baked goods), environmental monitoring, and biological samples.
• Metabolomics and Biomarker Research: Enables precise tracking and measurement of acrylamide and its metabolites in pharmacokinetic and toxicological studies.
• Method Development and Validation: Critical for developing robust, ISO-compliant analytical methods in quality control laboratories.
• Doping Control and Forensic Analysis: Employed as a reference standard in sports drug testing and forensic investigations for definitive identification.
• Pharmaceutical Impurity Profiling: Assists in the detection and quantification of potential genotoxic impurities (PGIs) in active pharmaceutical ingredients (APIs) and drug products.
• Environmental Fate Studies: Used as a tracer to study the degradation, absorption, and translocation of acrylamide in environmental matrices.

Basic Information

Product Name	Acrylamide-D5
CAS No.	108152-65-4
Molecular Formula	C3D5NO
Molecular Weight	76.11 g/mol
Synonyms	Acrylamide-d5; [2,3,3,3-D4,1-13C]Acrylamide; 2-Propenamide-d5; Deuterated Acrylamide (D5); Acrylamide (D5); Acrylamide-2,3,3,3-d4-1-13C; NSC 7789-d5; Acrylamide Internal Standard (D5)
EINECS	Contact for details

Quality Control

Our Acrylamide-D5 is manufactured under strict quality management systems to ensure the highest isotopic and chemical purity required for analytical standards. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results from advanced techniques including NMR, HPLC, and MS to confirm isotopic enrichment, chemical purity, and absence of interferents. We support compliance with ISO 17034 and GMP guidelines for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (NMR)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.