Description

4-Amino-1,2-Dihydroisoquinolin-1-One Hydrochloride is a high-purity, pharmaceutically relevant heterocyclic building block and synthetic intermediate. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) within the isoquinoline class.
• Organic Synthesis: Serves as a versatile precursor for constructing more complex heterocyclic frameworks and functionalized molecules.
• Biochemical Research: May be utilized as a tool compound or reference standard in biochemical assays and pharmacological studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Used in university and institutional laboratories for advanced organic synthesis and chemical methodology development.

Basic Information

Product Name	4-Amino-1,2-Dihydroisoquinolin-1-One Hydrochloride
CAS No.	108127-91-9
Molecular Formula	C9H9N2O·HCl
Molecular Weight	196.64 g/mol
Synonyms	4-Amino-1,2-dihydro-1-isoquinolinone hydrochloride; 4-Amino-1,2-dihydroisoquinolin-1-one HCl; 1(2H)-Isoquinolinone, 4-amino-1,2-dihydro-, hydrochloride; 4-Amino-1,2-dihydro-1-oxoisoquinoline hydrochloride; 4-Amino-1,2-dihydroisoquinolin-1-one monohydrochloride; 4-Aminoisoquinolin-1(2H)-one hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Amino-1,2-Dihydroisoquinolin-1-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), impurity profile, and residual solvents. Our quality commitment aligns with the standards expected for pharmaceutical intermediates, supporting both research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.