Description

5,6-Dihydro-4H-Cyclopenta[B]Thiophen-4-Ylamine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its functionalized cyclopentathiophene core, which serves as a critical scaffold in the synthesis of novel active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process scale-up teams within the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides and fungicides with unique modes of action.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors and conductive polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biological studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring a fused bicyclic amine scaffold.

Basic Information

Product Name	5,6-Dihydro-4H-Cyclopenta[B]Thiophen-4-Ylamine Hydrochloride
CAS No.	108046-27-1
Molecular Formula	C7H10ClNS
Molecular Weight	175.68 g/mol
Synonyms	4-Amino-5,6-dihydro-4H-cyclopenta[b]thiophene hydrochloride; 4-Cyclopenta[b]thienylamine hydrochloride; 5,6-Dihydro-4H-cyclopenta[b]thiophen-4-amine hydrochloride; 4-Amino-4,5,6,7-tetrahydrocyclopenta[b]thiophene hydrochloride; CPBTA-HCl; 108046-27-1; 4-Amino-4,5,6,7-tetrahydro-1-benzothiophene hydrochloride (related structure)
EINECS	Contact for details

Quality Control

Our 5,6-Dihydro-4H-Cyclopenta[B]Thiophen-4-Ylamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.