Description

3-Amino-5-Bromo-Thiophene-2-Carboxylic Acid Methyl Ester is a high-value heterocyclic building block, specifically a functionalized thiophene derivative, essential for advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the thiophene core for bioactivity.
• Material Science Research: Serves as a monomer or building block for conducting polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Institutional Research: Employed in university and government labs for fundamental research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	3-Amino-5-Bromo-Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	107818-55-3
Molecular Formula	C7H7BrN2O2S
Molecular Weight	263.11 g/mol
Synonyms	Methyl 3-Amino-5-bromothiophene-2-carboxylate; 5-Bromo-3-aminothiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-amino-5-bromo-, methyl ester; 3-Amino-5-bromothiophene-2-methyl carboxylate; Methyl 5-bromo-3-aminothiophene-2-carboxylate; 3-Amino-5-bromo-2-thiophenecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Bromo-Thiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.