Description

Methyl 3-Amino-5-(2-Chlorophenyl)Thiophene-2-Carboxylate is a high-purity, synthetically valuable heterocyclic building block, primarily utilized as a key intermediate in advanced pharmaceutical and agrochemical research and development. Its molecular structure, featuring both amino and ester functional groups on a thiophene core, makes it a versatile precursor for constructing complex molecules with targeted biological activity. This compound is essential for medicinal chemists and process development scientists in the life sciences sector seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the thiophene moiety can contribute to specific biological interactions.
• Material Science Research: Serves as a monomer or precursor for the development of advanced organic electronic materials, such as conductive polymers or organic semiconductors.
• Chemical Biology & Proteomics: Can be utilized as a derivatization agent or a tag in the study of biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	Methyl 3-Amino-5-(2-Chlorophenyl)Thiophene-2-Carboxylate
CAS No.	107818-29-1
Molecular Formula	C12H10ClNO2S
Molecular Weight	267.73 g/mol
Synonyms	Methyl 3-amino-5-(2-chlorophenyl)thiophene-2-carboxylate; 3-Amino-5-(2-chlorophenyl)thiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-amino-5-(2-chlorophenyl)-, methyl ester; Methyl 3-amino-5-(o-chlorophenyl)thiophene-2-carboxylate; 107818-29-1; Methyl 3-amino-5-(2-chlorophenyl)-2-thiophenecarboxylate
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Amino-5-(2-Chlorophenyl)Thiophene-2-Carboxylate is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard quality commitment includes HPLC purity ≥97% (with higher grades available), supported by full spectroscopic characterization (NMR, IR, MS). A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store the material under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.