Description

5-Amino-4-Cyano-N,n-Diethyl-3-Methylthiophene-2-Carboxamide is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both amino and cyano substituents on a thiophene core, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the thiophene scaffold contributes to biological activity.
• Organic Electronic Materials: Serves as a precursor for the synthesis of conjugated molecules and polymers for applications in organic light-emitting diodes (OLEDs) and semiconductors.
• Dye and Pigment Manufacturing: Acts as a building block for creating specialized heterocyclic dyes and functional colorants.
• Academic and Industrial R&D: Employed as a standard reagent in methodological studies and for exploring new chemical transformations in synthetic organic chemistry.
• Coordination Chemistry: The amino and carbonyl groups can act as ligands for metal complexes used in catalysis or material science.

Basic Information

Product Name	5-Amino-4-Cyano-N,n-Diethyl-3-Methylthiophene-2-Carboxamide
CAS No.	107815-98-5
Molecular Formula	C12H17N3OS
Molecular Weight	251.35 g/mol
Synonyms	5-Amino-4-cyano-3-methyl-N,N-diethylthiophene-2-carboxamide; 2-Carboxamide, 5-amino-4-cyano-N,N-diethyl-3-methylthiophene; 5-Amino-4-cyano-3-methylthiophene-2-N,N-diethylcarboxamide; 107815-98-5; 5-Amino-4-cyano-N,N-diethyl-3-methyl-2-thiophenecarboxamide; 3-Methyl-5-amino-4-cyano-N,N-diethylthiophene-2-carboxamide
EINECS	Contact for details

Quality Control

Our 5-Amino-4-Cyano-N,n-Diethyl-3-Methylthiophene-2-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.