Description

(Z)-3-(4-Ethoxyphenyl)-5-(3-Nitrobenzylidene)-2-Thioxothiazolidin-4-One is a specialized heterocyclic organic compound belonging to the rhodanine class, serving as a critical synthetic intermediate and a key scaffold in medicinal chemistry research. Its molecular architecture, featuring a nitrobenzylidene moiety, makes it a valuable precursor for developing novel bioactive molecules. This compound is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers focused on synthesizing compounds with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting enzymes and receptors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new pharmacophores with anti-microbial, anti-inflammatory, or anti-cancer properties.
• Chemical Biology Probe Development: Serves as a starting material for creating molecular probes to study biological pathways and protein interactions.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce the rhodanine-thioxothiazolidinone core into more complex molecular structures.
• Material Science Research: Investigated as a potential precursor for organic electronic materials due to its conjugated system.

Basic Information

Product Name	(Z)-3-(4-Ethoxyphenyl)-5-(3-Nitrobenzylidene)-2-Thioxothiazolidin-4-One
CAS No.	107621-35-2
Molecular Formula	C18H14N2O4S2
Molecular Weight	386.45 g/mol
Synonyms	5-[(Z)-(3-Nitrophenyl)methylene]-3-(4-ethoxyphenyl)-2-thioxo-4-thiazolidinone; 3-(4-Ethoxyphenyl)-5-[(Z)-(3-nitrophenyl)methylene]-2-thioxo-4-thiazolidinone; (Z)-3-(4-Ethoxyphenyl)-5-(3-nitrobenzylidene)rhodanine; (Z)-5-(3-Nitrobenzylidene)-3-(4-ethoxyphenyl)-2-thioxothiazolidin-4-one; 4-Thiazolidinone, 3-(4-ethoxyphenyl)-5-[(Z)-(3-nitrophenyl)methylene]-2-thioxo-; 107621-35-2; (Z)-Isomer of 3-(4-Ethoxyphenyl)-5-(3-nitrobenzylidene)-2-thioxothiazolidin-4-one
EINECS	Contact for details

Quality Control

Our (Z)-3-(4-Ethoxyphenyl)-5-(3-Nitrobenzylidene)-2-Thioxothiazolidin-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.