Description

(S)-Methyl 2-Amino-3-(6-Methoxy-1H-Indol-3-Yl)Propanoate CAS NO 107447-04-1 is a chiral, non-proteinogenic amino acid ester derivative of 6-methoxytryptophan. This compound serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis. It is primarily utilized by pharmaceutical research and development organizations for the synthesis of complex bioactive molecules, including potential drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.
• Peptidomimetic Synthesis: Used in the construction of peptide analogs and peptidomimetics where the incorporation of a modified tryptophan side chain is required.
• Asymmetric Synthesis: Employed as a starting material or chiral auxiliary in asymmetric catalytic reactions to induce stereoselectivity.
• Biochemical Research: Acts as a precursor or standard in biochemical studies investigating tryptophan metabolism and related enzymatic pathways.
• Agrochemical Development: Potential intermediate in the synthesis of advanced, chiral agrochemicals requiring specific stereochemistry for activity.
• Academic & Contract Research: Sourced by universities and CROs (Contract Research Organizations) for fundamental chemical research and custom synthesis projects.

Basic Information

Product Name	(S)-Methyl 2-Amino-3-(6-Methoxy-1H-Indol-3-Yl)Propanoate
CAS No.	107447-04-1
Molecular Formula	C₁₃H₁₆N₂O₃
Molecular Weight	248.28 g/mol
Synonyms	(S)-Methyl 6-Methoxytryptophanate; (S)-Methyl α-Amino-1H-indole-3-propanoate, 6-methoxy-; L-6-Methoxytryptophan methyl ester; Methyl (S)-2-amino-3-(6-methoxy-1H-indol-3-yl)propanoate; (S)-6-Methoxy-tryptophan methyl ester; 6-Methoxy-L-tryptophan methyl ester; (S)-α-Amino-1H-indole-3-propanoic acid, 6-methoxy-, methyl ester
EINECS	Contact for details

Quality Control

Our (S)-Methyl 2-Amino-3-(6-Methoxy-1H-Indol-3-Yl)Propanoate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be stored away from light. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.