Description

Aristolochic Acid E CAS NO 107259-48-3 is a specific, high-purity nitrophenanthrene carboxylic acid derivative belonging to the aristolochic acid family of natural products. This compound is of significant interest in advanced biochemical and pharmacological research due to its unique structural properties. It serves as a critical reference standard and building block for researchers and developers in the pharmaceutical, toxicology, and natural product chemistry sectors.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of aristolochic acid compounds in drug discovery and safety testing.
• Toxicological Studies: Serves as a key analyte in research investigating the nephrotoxic and carcinogenic mechanisms associated with aristolochic acids.
• Natural Product Research: Employed as a purified marker compound for the isolation, identification, and standardization of botanical extracts.
• Biochemical Pathway Analysis: Utilized in studies to understand the metabolic pathways and bioactivation of nitrophenanthrene derivatives.
• Quality Control Laboratories: Acts as a certified reference material (CRM) for method development and validation in analytical testing.
• Academic Research: Provides a well-defined chemical entity for synthetic chemistry, structural biology, and medicinal chemistry projects.

Basic Information

Product Name	Aristolochic Acid E
CAS No.	107259-48-3
Molecular Formula	C17H11NO7
Molecular Weight	341.27 g/mol
Synonyms	Aristolochic Acid E; 8-Methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic Acid; Aristolochic Acid V; Nitrophenanthrene carboxylic acid derivative; AA-E; Aristolochic acid E (AA-E); 6-Nitro-8-methoxyphenanthro[3,4-d][1,3]dioxole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of Aristolochic Acid E is produced and controlled under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods (HPLC, LC-MS, NMR). Our quality commitment ensures the material is suitable for its intended use in demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.