Description

Diethylisopropylsilyl Chloride is a versatile organosilicon reagent featuring a sterically hindered silyl protecting group. This compound is valued for its selective reactivity, making it a critical intermediate in sophisticated organic synthesis and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the protection of alcohols and other functional groups.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly for protecting hydroxyl groups during multi-step reactions.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where selective protection is required.
• Polymer & Material Science: Serves as a modifying agent or cross-linker in the development of specialty silicones and silicon-based polymers.
• Organic Synthesis Reagent: Essential for academic and industrial R&D in constructing complex natural products and novel organic compounds.
• Peptide & Carbohydrate Chemistry: Employed for the temporary protection of sensitive functional groups in biomolecule synthesis.
• Production of Silicon-Containing Monomers: Acts as a precursor for other functionalized silanes used in surface modification and coatings.

Basic Information

Product Name	Diethylisopropylsilyl Chloride
CAS No.	107149-56-4
Molecular Formula	C7H17ClSi
Molecular Weight	164.75 g/mol
Synonyms	Chlorodiethylisopropylsilane; Diethyl(isopropyl)silyl chloride; Isopropyldiethylsilyl chloride; (Isopropyl)diethylchlorosilane; DEIPS-Cl; 1-Chloro-1-diethyl-1-isopropylsilane; Silane, chlorodiethylisopropyl-; (i-Pr)Et2SiCl
EINECS	Contact for details

Quality Control

Our Diethylisopropylsilyl Chloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot is analyzed using advanced techniques including GC, NMR, and titration to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (GC Area %)	≥ 98.0%
Density (at 20°C)	0.88 - 0.92 g/mL
Refractive Index (n20D)	1.430 - 1.440

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.