Description

7-Deaza-Da Cep CAS NO 107134-59-8 is a high-purity nucleoside analog, specifically a 7-deaza-2'-deoxyadenosine derivative, designed for advanced research and development. This compound is critical for applications in oligonucleotide synthesis, where it serves as a modified building block to enhance stability and alter hybridization properties. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, molecular diagnostics, and academic biochemistry for probing nucleic acid structure and function.

Application

• Oligonucleotide Synthesis: As a modified phosphoramidite for the solid-phase synthesis of DNA and RNA analogs.
• Antisense and siRNA Research: Incorporation into therapeutic oligonucleotides to improve nuclease resistance and pharmacokinetic profiles.
• Molecular Probes and Diagnostics: Used in the development of fluorescent probes and primers for PCR and sequencing applications.
• Structural Biology Studies: A tool for investigating nucleic acid-protein interactions and duplex stability.
• Medicinal Chemistry: A key intermediate in the synthesis of novel nucleoside-based antiviral or anticancer agents.
• Biochemical Research: Substrate or inhibitor for studies involving DNA polymerases and other nucleic acid-metabolizing enzymes.

Basic Information

Item	Detail
Product Name	7-Deaza-Da Cep
CAS No.	107134-59-8
Molecular Formula	C11H14N4O4
Molecular Weight	266.25 g/mol
Synonyms	7-Deaza-2'-deoxyadenosine; 7-Deaza-dA; 7-Deaza-2'-deoxy-7-adenine; Tubercidin 2'-deoxyriboside; 4-Amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-(2-deoxy-β-D-erythro-pentofuranosyl)-
EINECS	Contact for details

Quality Control

Our 7-Deaza-Da Cep is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. We ensure compliance with relevant industry standards for research-grade chemicals. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and moisture absorption. Allow the container to reach room temperature in a desiccator before opening to minimize exposure to humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.