Description

3-Hydroxy-n-[2-Phenyl-2-(2-Thienyl)Ethenyl]-5-(Trifluoromethyl)Benzo[B]Thiophene-2-Carboxamide is a high-purity, complex heterocyclic compound featuring a benzothiophene core functionalized with a trifluoromethyl group and a unique carboxamide side chain. This specialized structure makes it a valuable advanced pharmaceutical intermediate and a critical building block in organic synthesis for research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor-binding profiles.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex molecular architectures, leveraging its reactive hydroxyl and amide functionalities.
• Material Science Research: Investigated as a potential component in the development of organic semiconductors or specialty polymers due to its conjugated thiophene and benzothiophene systems.
• Agrochemical Intermediate: May be employed in the research and development of new crop protection agents, where the trifluoromethyl group can enhance biological activity and stability.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in pharmaceutical development.

Basic Information

Product Name	3-Hydroxy-n-[2-Phenyl-2-(2-Thienyl)Ethenyl]-5-(Trifluoromethyl)Benzo[B]Thiophene-2-Carboxamide
CAS No.	107008-29-7
Molecular Formula	C22H14F3NO2S2
Molecular Weight	453.48 g/mol
Synonyms	3-Hydroxy-N-[2-phenyl-2-(thiophen-2-yl)vinyl]-5-(trifluoromethyl)benzo[b]thiophene-2-carboxamide; 3-Hydroxy-5-(trifluoromethyl)-N-[2-phenyl-2-(2-thienyl)ethenyl]-2-benzothiophenecarboxamide; 3-Hydroxy-5-(trifluoromethyl)-N-[(E)-2-phenyl-2-(thiophen-2-yl)vinyl]-1-benzothiophene-2-carboxamide; Benzo[b]thiophene-2-carboxamide, 3-hydroxy-N-[2-phenyl-2-(2-thienyl)ethenyl]-5-(trifluoromethyl)-; CAS 107008-29-7
EINECS	Contact for details

Quality Control

Our production of 3-Hydroxy-n-[2-Phenyl-2-(2-Thienyl)Ethenyl]-5-(Trifluoromethyl)Benzo[B]Thiophene-2-Carboxamide adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.