Description

2-Bromothiophen-3-Amine is a versatile brominated thiophene derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amine and a bromine substituent on the thiophene ring, makes it a valuable precursor for constructing complex heterocyclic systems and functional materials. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, enabling the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the thiophene scaffold for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials and emissive layer components in display and lighting technologies.
• Polymer and Material Science: Building block for conductive polymers, organic semiconductors, and advanced functional materials.
• Ligand and Catalyst Development: Useful in the synthesis of novel ligands for transition metal catalysis and organocatalysts.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and constructing complex molecular architectures in academic and industrial R&D.

Basic Information

Product Name	2-Bromothiophen-3-Amine
CAS No.	106944-13-2
Molecular Formula	C4H4BrNS
Molecular Weight	178.05 g/mol
Synonyms	3-Amino-2-bromothiophene; 2-Bromo-3-thiophenamine; 2-Bromothiophene-3-amine; 2-Bromo-3-aminothiophene; 3-Thiophenamine, 2-bromo-; 2-Bromothien-3-ylamine; 2-Bromo-1,3-thiazol-5-amine (tautomeric form); 2-Bromo-3-thienylamine
EINECS	Contact for details

Quality Control

Our 2-Bromothiophen-3-Amine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.