Description

[6As,(-)]-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aα-Octahydro-10α-Isothiocyanato-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole is a high-purity, complex organic compound featuring a unique isothiocyanate functional group within a fused polycyclic framework. This structural motif makes it a valuable advanced intermediate for pharmaceutical research and the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to explore new chemical entities and develop targeted therapies.

Application

• Pharmaceutical Intermediate: Key building block for the research and development of new drug candidates, particularly in oncology and CNS disorders.
• Chemical Biology Probe: Utilized in proteomics and target identification studies due to the reactive isothiocyanate group for covalent binding.
• Agrochemical Research: Serves as a precursor in the synthesis of novel pesticides and herbicides with potential new modes of action.
• Material Science: Investigated as a monomer or cross-linking agent for the development of specialty polymers with tailored properties.
• Academic Research: Used in universities and research institutes for methodological studies in organic synthesis and natural product analog development.

Basic Information

Product Name	[6As,(-)]-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aα-Octahydro-10α-Isothiocyanato-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole
CAS No.	106865-64-9
Molecular Formula	C22H28N2S
Molecular Weight	352.54 g/mol
Synonyms	(-)-9α-Ethenyl-10α-isothiocyanato-6,6,9-trimethyl-2,3,6,6a,7,8,9,10,10a,10b-decahydronaphtho[1,2,3-cd]indole; 9α-Ethenyl-10α-isothiocyanato-6,6,9-trimethyl-1,2,3,4,4a,5,6,10b-octahydronaphtho[1,2,3-cd]indole; NSC 339587; Isothiocyanate derivative of vinorelbine precursor; Complex indole isothiocyanate
EINECS	Contact for details

Quality Control

Our [6As,(-)]-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aα-Octahydro-10α-Isothiocyanato-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.