Description

1-Acetyl-5-Bromoindolin-3-One is a high-purity, synthetically valuable brominated indolinone derivative. This compound serves as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used for constructing complex indole and indoline-based molecular frameworks in medicinal chemistry research.
• Agrochemical Research: Employed in the development of new herbicides and pesticides with novel modes of action.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: Serves as a standard or starting material in university laboratories and CROs (Contract Research Organizations) for method development and discovery chemistry.

Basic Information

Product Name	1-Acetyl-5-Bromoindolin-3-One
CAS No.	106698-07-1
Molecular Formula	C10H8BrNO2
Molecular Weight	254.08 g/mol
Synonyms	5-Bromo-1-acetylindolin-3-one; 5-Bromo-1-acetyl-2,3-dihydro-1H-indol-3-one; 1-Acetyl-5-bromo-2,3-dihydro-1H-indol-3-one; 5-Bromo-3-oxo-1-acetylindoline; 3-Acetyl-5-bromoindolin-2-one (tautomer); 5-Bromo-1-acetyl-3-indolinone; 106698-07-1; 1H-Indol-3-one, 5-bromo-1-acetyl-2,3-dihydro-
EINECS	Contact for details

Quality Control

Our 1-Acetyl-5-Bromoindolin-3-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP environments for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.