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5-Chloro-3-[1-((Imidazolidin-2-One-1-Yl)-Ethyl)-1,2,5,6-Tetrahydropyridin-4-Yl]-1-(4-Fluorophenyl)-Indole CAS NO 106516-54-5


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CAS No.:106516-54-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Chloro-3-[1-((Imidazolidin-2-One-1-Yl)-Ethyl)-1,2,5,6-Tetrahydropyridin-4-Yl]-1-(4-Fluorophenyl)-Indole is a sophisticated heterocyclic organic compound of significant interest in advanced chemical synthesis. This molecule serves as a critical intermediate or building block for the research and development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
  • Chemical Biology Probe Development: Serves as a core structure for creating molecular probes to study specific biological targets and pathways.
  • Contract Synthesis: Supplied to CROs and CDMOs for custom synthesis projects requiring complex heterocyclic frameworks.
  • Reference Standard: Utilized as an analytical standard for quality control and method development in API manufacturing.
  • Preclinical Development: Employed in the production of compounds for toxicology and early-stage animal studies.

Basic Information

Item Details
Product Name 5-Chloro-3-[1-((Imidazolidin-2-One-1-Yl)-Ethyl)-1,2,5,6-Tetrahydropyridin-4-Yl]-1-(4-Fluorophenyl)-Indole
CAS No. 106516-54-5
Molecular Formula C24H24ClFN4O
Molecular Weight 438.93 g/mol
Synonyms 5-Chloro-3-[1-[(2-oxoimidazolidin-1-yl)ethyl]-1,2,5,6-tetrahydropyridin-4-yl]-1-(4-fluorophenyl)indole; 1-(4-Fluorophenyl)-5-chloro-3-[1-[(2-oxoimidazolidin-1-yl)ethyl]-1,2,5,6-tetrahydropyridin-4-yl]indole; 106516-54-5; UNII-8V8P8W4J7B; 8V8P8W4J7B; CHEMBL3183450; BDBM50391248; AKOS025147424
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Quality Control

Our 5-Chloro-3-[1-((Imidazolidin-2-One-1-Yl)-Ethyl)-1,2,5,6-Tetrahydropyridin-4-Yl]-1-(4-Fluorophenyl)-Indole is produced under a strict quality management system. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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