Description

1H-Indole, 5-Nitro-3-(1,2,3,6-Tetrahydro-1-Methyl-4-Pyridinyl)- is a specialized heterocyclic organic compound of significant interest in advanced chemical synthesis. This molecule matters as a key synthetic intermediate, offering a versatile scaffold for constructing complex pharmacologically active structures. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and fine chemical products.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the research and synthesis of potential drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) due to its indole and tetrahydro-pyridine motifs.
• Organic Synthesis: Acts as a versatile precursor for the preparation of more complex heterocyclic compounds and functionalized indole derivatives.
• Biochemical Research: Employed in the study of enzyme inhibitors and receptor ligands, given its structural similarity to various biologically active molecules.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals for advanced material science and agrochemical research.

Basic Information

Product Name	1H-Indole, 5-Nitro-3-(1,2,3,6-Tetrahydro-1-Methyl-4-Pyridinyl)-
CAS No.	106516-27-2
Molecular Formula	C14H15N3O2
Molecular Weight	257.29 g/mol
Synonyms	5-Nitro-3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole; 3-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-5-nitro-1H-indole; 5-Nitro-3-(1-methyl-4-piperidinylidene)indole; 1-Methyl-4-(5-nitro-1H-indol-3-yl)-1,2,3,6-tetrahydropyridine; 106516-27-2; 5-Nitro-3-(1-methyl-4-piperidenyl)indole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with typical purity levels suitable for research and development purposes. Certificates of Analysis (COA) detailing identity, purity, and related substance profiles are available upon request. Our quality system supports the needs of cGMP-compliant research and development activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Related Substances (HPLC)	Individual impurity ≤1.0%
Total Impurities (HPLC)	≤5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.