Description

1-Chloro-5-Methoxyisoquinoline is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular scaffold, featuring both chloro and methoxy substituents, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research institutions and pharmaceutical developers for the creation of novel active compounds and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced functional materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the isoquinoline moiety into more complex molecular architectures.
• Academic & R&D: Utilized in university and corporate laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	1-Chloro-5-Methoxyisoquinoline
CAS No.	106462-85-5
Molecular Formula	C₁₀H₈ClNO
Molecular Weight	193.63 g/mol
Synonyms	5-Methoxy-1-chloroisoquinoline; 1-Chloro-5-methoxy-isoquinoline; Isoquinoline, 1-chloro-5-methoxy-; 106462-85-5; 1-Chloro-5-methoxy-isoquinoline; 5-Methoxy-1-chloro-isoquinoline
EINECS	Contact for details

Quality Control

Our 1-Chloro-5-Methoxyisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.