Description

1H-Benzimidazol-5-Ylmethanol is a versatile benzimidazole derivative, a crucial heterocyclic building block in advanced organic synthesis. Its core value lies in providing a functionalized scaffold essential for constructing complex molecules with targeted biological or material properties. This high-purity intermediate is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in therapeutic areas targeting enzymes and receptors where the benzimidazole core is privileged.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides, herbicides, and plant growth regulators that incorporate the benzimidazole pharmacophore.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds due to its electron-rich aromatic system.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-fidelity functionalization of the benzimidazole ring system.

Basic Information

Product Name	1H-Benzimidazol-5-Ylmethanol
CAS No.	106429-29-2
Molecular Formula	C8H8N2O
Molecular Weight	148.16 g/mol
Synonyms	5-(Hydroxymethyl)-1H-benzimidazole; 1H-Benzimidazole-5-methanol; 5-(Hydroxymethyl)benzimidazole; Benzimidazol-5-ylmethanol; 5-Hydroxymethylbenzimidazole; 5-BIM-OH; (1H-Benzimidazol-5-yl)methanol; NSC 405124
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazol-5-Ylmethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.