Description

1-(2-Cyclohexyl-2-Oxoethyl)-5-Methoxy-2-Methyl-1H-Indole-3-Acetic Acid is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate with significant commercial and research value. This compound is critical for the synthesis of advanced pharmaceutical agents targeting inflammation and pain, offering a key building block for drug development. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) engaged in the development of novel therapeutic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel NSAIDs and other therapeutic agents.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex, biologically active molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1-(2-Cyclohexyl-2-Oxoethyl)-5-Methoxy-2-Methyl-1H-Indole-3-Acetic Acid
CAS No.	106287-92-7
Molecular Formula	C20H25NO4
Molecular Weight	343.42 g/mol
Synonyms	5-Methoxy-2-methyl-1-(2-oxo-2-cyclohexylethyl)-1H-indole-3-acetic acid; 1H-Indole-3-acetic acid, 1-(2-cyclohexyl-2-oxoethyl)-5-methoxy-2-methyl-; Cyclohexyl NSAID Intermediate; Indole-3-acetic acid derivative; [106287-92-7]
EINECS	Contact for details

Quality Control

Our 1-(2-Cyclohexyl-2-Oxoethyl)-5-Methoxy-2-Methyl-1H-Indole-3-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring material suitable for advanced research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.