Description

(+)-(6R)-2,6-Diamino-4,5,6,7-Tetrahydrobenzothiazole is a high-purity, chiral benzothiazole derivative of significant interest in advanced pharmaceutical synthesis. This compound matters as a critical chiral building block and intermediate for the development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research. Pharmaceutical R&D teams and fine chemical manufacturers need this material for its role in constructing complex molecular architectures with high stereochemical fidelity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and psychiatric applications.
• Asymmetric Synthesis: Utilized as a building block in stereoselective synthesis to introduce the tetrahydrobenzothiazole core with defined (R)-configuration at the 6-position.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the creation of targeted compound libraries.
• Precursor for Bioactive Molecules: Used in the synthesis of potential dopamine receptor ligands and other neuroactive compounds.
• Fine Chemical Production: Employed in contract manufacturing and custom synthesis for producing high-value, specialized chemicals.

Basic Information

Product Name	(+)-(6R)-2,6-Diamino-4,5,6,7-Tetrahydrobenzothiazole
CAS No.	106092-11-9
Molecular Formula	C7H11N3S
Molecular Weight	169.25 g/mol
Synonyms	(6R)-2,6-Diamino-4,5,6,7-tetrahydro-1,3-benzothiazole; (R)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole; (+)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole; (6R)-2,6-Diaminotetrahydrobenzothiazole; Pramipexole Intermediate; Pramipexole Related Compound; Benzothiazole, 2,6-diamino-4,5,6,7-tetrahydro-, (6R)-
EINECS	Contact for details

Quality Control

Our (+)-(6R)-2,6-Diamino-4,5,6,7-Tetrahydrobenzothiazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the material should be stored under an inert atmosphere or in a desiccated environment to maintain stability. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.