Description

Diexo-3-Amino-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a rigid, functionalized bicyclic scaffold. This compound is valued for its role as a key chiral building block in the synthesis of complex, biologically active molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including protease inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Protease Inhibitor Development: Serves as a core structural component in the research and production of protease inhibitors for antiviral and other therapeutic applications.
• Asymmetric Synthesis: Utilized as a starting material or reagent in asymmetric catalytic reactions to introduce stereochemical complexity.
• Peptidomimetics Research: Used to construct constrained peptide analogs (peptidomimetics) that mimic natural peptides with enhanced metabolic stability.
• Chemical Biology & Probe Development: Employed in the design and synthesis of chemical probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied for custom synthesis projects requiring high-fidelity, stereochemically defined bicyclic frameworks.

Basic Information

Product Name	Diexo-3-Amino-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester
CAS No.	105786-35-4
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	(1R,2S,3R,4S)-3-Aminobicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester; Ethyl (1R,2S,3R,4S)-3-aminobicyclo[2.2.1]heptane-2-carboxylate; exo-3-Aminonorbornane-2-carboxylic acid ethyl ester; 3-Amino-2-norbornanecarboxylic acid ethyl ester, endo,exo-; Bicyclo[2.2.1]heptane-2-carboxylic acid, 3-amino-, ethyl ester, (1R,2S,3R,4S)-
EINECS	Contact for details

Quality Control

Our Diexo-3-Amino-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.