Description

Diendo-3-Amino-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid Ethyl Ester is a high-purity, functionalized bicyclic compound that serves as a critical chiral building block in advanced organic synthesis. Its unique strained norbornene framework, combined with both amino and ester functionalities, makes it a versatile intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development in pharmaceutical chemistry, agrochemicals, and materials science, where it is used to develop novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in developing central nervous system (CNS) agents and antiviral compounds.
• Agrochemical Research: Used in creating advanced, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Science: Employed in the synthesis of specialty polymers and resins with tailored thermal and mechanical properties via ring-opening metathesis polymerization (ROMP).
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and protein interactions due to its reactive handle and rigid structure.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	Diendo-3-Amino-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid Ethyl Ester
CAS No.	105786-34-3
Molecular Formula	C11H17NO2
Molecular Weight	195.26 g/mol
Synonyms	Ethyl 3-Amino-2,5-norbornadiene-2-carboxylate; Ethyl 3-Aminobicyclo[2.2.1]hepta-2,5-diene-2-carboxylate; Diendo-Ethyl 3-Aminobicyclo[2.2.1]hept-5-ene-2-carboxylate; 2-Carboxy-3-aminonorborn-5-ene ethyl ester; 3-Amino-2-norbornene-2-carboxylic acid ethyl ester; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-amino-, ethyl ester, endo-; (1R,2S,3R,4S)-Ethyl 3-aminobicyclo[2.2.1]hept-5-ene-2-carboxylate
EINECS	Contact for details

Quality Control

Our Diendo-3-Amino-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (Diendo isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.