Description

2-Acetyl-3-Amino-5-Phenylthiophene is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of novel pharmaceuticals and specialty chemicals, enabling the construction of complex molecular architectures. It is primarily needed by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic cores.
• Agrochemical Synthesis: Serves as a building block in the creation of novel herbicides, fungicides, and insecticides, leveraging its unique thiophene-based structure.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene ring and functional groups.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized dyes and organic pigments, where the acetyl and amino groups allow for further chemical modifications.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including novel cyclization and cross-coupling reactions.
• Ligand and Catalyst Development: The amino and carbonyl functionalities make it a candidate for designing novel chelating ligands and organocatalysts.

Basic Information

Item	Details
Product Name	2-Acetyl-3-Amino-5-Phenylthiophene
CAS No.	105707-24-2
Molecular Formula	C12H11NOS
Molecular Weight	217.29 g/mol
Synonyms	1-(3-Amino-5-phenylthiophen-2-yl)ethanone; 2-Acetyl-3-amino-5-phenylthiophene; 3-Amino-5-phenylthiophene-2-yl methyl ketone; 2-Acetylamino-5-phenylthiophene (common misnomer); Ethanone, 1-(3-amino-5-phenyl-2-thienyl)-; 3-Amino-α-oxo-5-phenyl-2-thiopheneacetamide precursor; 5-Phenyl-3-aminothiophene-2-carboxaldehyde derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Acetyl-3-Amino-5-Phenylthiophene is produced under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets the stringent requirements for research and scale-up applications. A detailed Certificate of Analysis (COA) documenting purity, impurities, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.