Description

Cyclopentanecarboxamide, 3-Mercapto-, cis- (9Ci) is a specialized chiral building block featuring both a carboxamide and a reactive mercapto (thiol) functional group on a cyclopentane scaffold. This compound matters as a high-value intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and development where its unique stereochemistry and functional handles are critical. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional ligands.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of potential drug candidates, especially those targeting enzyme inhibition or requiring specific three-dimensional orientation.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis, leveraging the thiol group for metal coordination.
• Peptidomimetics Research: The cis-cyclopentane structure acts as a conformationally restricted scaffold to mimic peptide turns in medicinal chemistry.
• Agrochemical Development: Employed in creating novel active ingredients for crop protection with specific stereochemical requirements.
• Chemical Biology Probes: Utilized to develop activity-based probes or affinity tags due to the reactive thiol functionality.
• Material Science: Potential monomer or cross-linking agent for polymers requiring specific mechanical or chemical properties.

Basic Information

Product Name	Cyclopentanecarboxamide, 3-Mercapto-, cis- (9Ci)
CAS No.	105676-07-1
Molecular Formula	C7H11NOS
Molecular Weight	157.23 g/mol
Synonyms	cis-3-Mercaptocyclopentanecarboxamide; (1S,3R)-3-Mercaptocyclopentanecarboxamide; (1R,3S)-3-Mercaptocyclopentanecarboxamide; 3-Mercaptocyclopentanecarboxamide; 3-Thiocyclopentanecarboxamide; cis-3-Mercaptocyclopentane-1-carboxamide; Cyclopentanecarboxamide, 3-mercapto-, (1R,3S)-rel-; 105676-07-1
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboamide, 3-Mercapto-, cis- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its easily oxidized nature, minimize headspace and exposure to air after opening.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.