Description

Cyclopentanecarboxylic Acid, 3-Mercapto-, cis- (9Ci) is a specialized chiral building block featuring both a carboxylic acid and a thiol (mercapto) functional group on a cyclopentane scaffold. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research, particularly for introducing sulfur-containing moieties and constrained ring systems. It is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), peptide mimetics, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of protease inhibitors, enzyme modulators, and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced biological activity.
• Peptidomimetics & Bioactive Compounds: Used to construct conformationally restricted peptide analogs and other bioactive molecules.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Material Science Research: Potential monomer for specialty polymers or functional materials requiring specific chemical handles.
• Chemical Biology Probes: Utilized in the synthesis of probes for studying enzyme mechanisms or protein interactions.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 3-Mercapto-, cis- (9Ci)
CAS No.	105676-05-9
Molecular Formula	C6H10O2S
Molecular Weight	146.21 g/mol
Synonyms	cis-3-Mercaptocyclopentanecarboxylic Acid; (1R,3S)-3-Mercaptocyclopentanecarboxylic Acid; (1S,3R)-3-Mercaptocyclopentanecarboxylic Acid; 3-Mercaptocyclopentane-1-carboxylic acid; 3-Sulfanylcyclopentane-1-carboxylic acid; cis-3-Thiolcyclopentanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 3-Mercapto-, cis- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure identity, strength, and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay, enantiomeric excess, and impurity profiles. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation of the thiol group and ensure long-term stability. Keep the container in a cool, dry, and well-ventilated area, separate from oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.