Description

1-[(1-Chloro-5-Isoquinolinyl)Sulfonyl]Hexahydro-1H-1,4-Diazepine is a high-value, heterocyclic organic compound featuring a unique isoquinoline and diazepine scaffold, making it a critical intermediate for advanced chemical synthesis. Its core value lies in enabling the development of novel pharmacologically active molecules, particularly in medicinal chemistry and drug discovery research. This compound is essential for B2B clients in the pharmaceutical, agrochemical, and specialty fine chemical industries who require reliable, high-purity building blocks for their R&D and process development pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new bioactive chemical space.
• Agrochemical Development: Acts as a building block for creating novel active ingredients in crop protection and pest management solutions.
• Chemical Biology Probes: Utilized in the development of molecular probes and tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-[(1-Chloro-5-Isoquinolinyl)Sulfonyl]Hexahydro-1H-1,4-Diazepine
CAS No.	105628-70-4
Molecular Formula	C₁₆H₁₈ClN₃O₂S
Molecular Weight	351.85 g/mol
Synonyms	1-[(1-Chloro-5-isoquinolinyl)sulfonyl]hexahydro-1H-1,4-diazepine; 1-(1-Chloro-5-isoquinolinylsulfonyl)hexahydro-1H-1,4-diazepine; Hexahydro-1-[(1-chloro-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepine; 1,4-Diazepine, hexahydro-1-[(1-chloro-5-isoquinolinyl)sulfonyl]-; 1-(1-Chloro-5-isoquinolinylsulfonyl)perhydro-1,4-diazepine; 1-(1-Chloro-5-isoquinolinylsulfonyl)-1,4-diazepane; CAS 105628-70-4
EINECS	Contact for details

Quality Control

Our 1-[(1-Chloro-5-Isoquinolinyl)Sulfonyl]Hexahydro-1H-1,4-Diazepine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable supply for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.