Description

Isoquinoline-5-Sulphonyl Chloride Hydrochloride is a specialized organic intermediate of significant importance in advanced chemical synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), fine chemicals, and novel agrochemicals where the introduction of a sulphonyl chloride moiety is required.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive sulphonyl chloride group.
• Dye and Pigment Manufacturing: Serves as an intermediate for creating specialized dyes and functional colorants with specific light-fastness or chemical properties.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as polymers or liquid crystals, requiring specific heterocyclic architectures.
• Bioconjugation Chemistry: Acts as a reagent for modifying biomolecules (e.g., peptides, proteins) in biochemical research and diagnostic assay development.
• Chemical Biology Probes: Utilized to create activity-based probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Isoquinoline-5-Sulphonyl Chloride Hydrochloride
CAS No.	105627-79-0
Molecular Formula	C9H7Cl2NO2S
Molecular Weight	264.13 g/mol
Synonyms	5-Isoquinolinesulfonyl chloride hydrochloride; Isoquinoline-5-sulfonyl chloride, hydrochloride; 5-(Chlorosulfonyl)isoquinoline hydrochloride; 1-Azanaphthalene-5-sulfonyl chloride hydrochloride; Isoquinoline-5-sulfonic acid chloride hydrochloride; 5-Chlorosulfonylisoquinoline hydrochloride; 5-Isoquinolinesulphonyl chloride hydrochloride
EINECS	Contact for details

Quality Control

Our Isoquinoline-5-Sulphonyl Chloride Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global customer base in the fine chemical and pharmaceutical sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to maintain stability and purity. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%
Solubility	Soluble in common organic solvents (e.g., DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.