Description

4-(3-Bromo-Phenyl)-Thiazol-2-Ylamine is a high-purity brominated thiazole derivative, a key organic intermediate valued for its versatile reactivity and role in constructing complex heterocyclic scaffolds. Its primary commercial importance lies in enabling the synthesis of advanced pharmaceutical compounds and specialized agrochemicals, where its specific bromine substitution pattern is critical for activity. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly for kinase inhibitors, anti-inflammatory agents, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new-generation fungicides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in the study of biological pathways and protein interactions.
• Dye & Pigment Intermediate: Acts as a key component in the synthesis of specialized heterocyclic dyes and functional pigments.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up production for clients.

Basic Information

Product Name	4-(3-Bromo-Phenyl)-Thiazol-2-Ylamine
CAS No.	105512-81-0
Molecular Formula	C9H7BrN2S
Molecular Weight	255.13 g/mol
Synonyms	2-Amino-4-(3-bromophenyl)thiazole; 4-(3-Bromophenyl)-1,3-thiazol-2-amine; 4-(3-Bromophenyl)-2-thiazolamine; 4-(m-Bromophenyl)-2-aminothiazole; 2-Thiazolamine, 4-(3-bromophenyl)-; 4-(3-Bromophenyl)thiazol-2-amine; 3-Bromo-4-(2-aminothiazol-4-yl)benzene (less common); 105512-81-0
EINECS	Contact for details

Quality Control

Every batch of 4-(3-Bromo-Phenyl)-Thiazol-2-Ylamine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC for assay and impurity profiling, NMR and IR for structural confirmation, and other relevant physicochemical tests. Our quality commitment supports applications requiring GMP-grade intermediates and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.